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Can you stop hormone replacement cold turkey? Going Off Menopausal Hormone Therapy. As women who have been diagnosed with breast cancer know firsthand, it is possible—and from a medical perspective, perfectly okay—to stop hormones cold turkey. In fact, about half of all women who stop taking hormones cold turkey will do just fine. Can stress cause hormonal imbalance? Stress can cause hormonal imbalance in women. Many women are affected negatively by hormonal imbalance. So, a brain structure called the Hypothalamus controls hormonal secretions from the ovaries and all other glands in the body. How long will hot flashes last after stopping HRT? How long do hot flashes last ? It used to be said that menopause-related hot flashes fade away after six to 24 months. But for many women, hot flashes and night sweats often last seven years and may go on for 11 years or more.
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